★Lemon Tree – Citrus limonum (bark): Contains seselin (coumarin) with cytotoxic properties and potent anti-inflammatory agents (serrapeptase, a proteolytic enzyme). Serrapeptase is a naturally-occurring, physiological agent with no inhibitory effects on prostaglandins and is devoid of gastrointestinal side effects.

★Maidenhair Tree – Ginkgo biloba (buds): Acacetin (AC), one of the three flavonoid compounds with same flavone ring structure but different substitution as linarin (LN) and linarin acetate (LA), has been shown to be effective against human prostate cancer (PCA) LNCaP and DU145 cells. AC showed more potent anticancer efficacy among these three flavonoids, which was diminished when its flavone ring was modified by disaccharide rhamnose substitution at C7 (LN) or acetylation of this substituted group (LA). These findings revealed for the first time the structural determinants in anticancer efficacy and mechanisms of these flavonoids against human PCA cells.

★★Maize – Zea mais (embryonic germinating seed-rootlets): Use as an anti-inflammatory for prostate adenoma and androgen hormone-dependent/independent cancers and other androgen conditions, hyper or hypo functions. (Refer to section on Silver Birch embryonic seeds to find out more about biological activities of plant growth, immune and stress hormones.)

★Mountain Pine – Pinus montana (buds): Chamazulene is a natural profen with anti-inflammatory activity similar to fully synthetic ibuprofen drug substances; used as prostaglandin inhibitor; also contains taxifolin, an anti-inflammatory; potent antioxidant (stronger than that of tocopherol and carotene); anti-mutagenic; anti-tumor; anticancer; antitumor in breast, colon, gastric, pancreas, prostate; apoptotic. Oligomeric Proanthocyanidins. OPC’s are much more effective at low doses than aspirin. Anticancer, Antitumor Breast, Colon, Gastric, Pancreas, Prostate. Apoptotic.

★Oriental Plane Tree – Platanus orientalis (buds): Contains Kaempferol to disrupt estrogen receptors; induces apoptosis; as aromatase inhibitor; antitumor; inhibitor of Sulfotransferase 1A1 (or P-PST).

Kaempherol is the chemical in oriental plane tree buds responsible for making estrogen less carcinogenic by working on the receptor without taking good estrogen out. This activity has a positive effect on the body being estriol there are three major types of estrogen being estriol estradiol and estrogen.

Kaempferol is a sterol with both estrogenic and anti-estrogenic activities, which are biphasic (bipolar actions) in response on estrogen receptors. Kaempferol induces strong antiproliferative effect; exhibits cytotoxicity against breast cancer, endometrial cancer, testicular cancer, prostate cancer, anticancer, anticarcinomic, antileukemic, antimelanomic, antitumor, apoptotic, cytotoxic. Kaempferol can help to fight cancer by reducing the resistance of cancer cells to anti-cancer drugs such as vinblastine and paclitaxel. Indole Acetic Acid IAA Auxins, which are found in Auxins, stimulate an enzyme that makes estrogen less effective, thus reducing the risk for breast and prostate cancer.Two Kaempferol coumaroyl glycosides (i.e., Platanoside and Tiliroside, Kaempferol 3-O-alpha-L-(2"-E-p-coumaroyl)-rhamnopyranoside, as well as the flavonoids Kaempferol 3-O-beta-D-(6"-E-p-coumaroyl)-glucopyranoside, which disrupt estrogen receptors. Abscisic Acid (ABA), a plant stress hormone is a naturally occurring compound in embryonic plants. It is a sesquiterpenoid (15-carbon). Abscisic acid is a close relative of vitamin A, known for its anti-tumor activity.

The estrogenic and/or anti-estrogenic biphasic effects and now because it contains also plant stem cells adaptive bipolar actions in differentiation becoming specialized of kaempferol, which can confirm its potency as a preventive agent against estrogen-related diseases. Kaempferol and quercetin decrease the binding affinities of ER cancers.

Several putative mechanisms that could account for the hypothesized chemopreventive effects of phytoestrogens have been proposed. Most prominently, phytoestrogens have been suggested to exert strong anti-estrogenic effects, thereby inhibiting development of hormone-related cancers. All other phytoestrogens, including the flavonoids that are present in many foods, showed only agonistic activity. In previous in vitro studies involving ER, only agonistic or at best partial antagonistic activities instead of complete antagonistic activities were reported.

Several other mechanisms for the proposed chemopreventive effects of flavonoids have been suggested, including induction of cancer cell differentiation, inhibition of protein tyrosine kinases, suppression of angiogenesis, and direct antioxidant effects.

★Rosemary – Rosmarinus officinalis (young shoots): Contains Carnosic-Acid 73.9% and Carnosol 14.7% (major diterpenes), anticancer phytochemicals; antimutagenic; anti-inflammatory; antiplatelet; apoptotic; chemoprotective. Due to its antioxidant and anti-inflammatory properties, Carnosic acid prevents the migration of human aortic smooth muscle cells by inhibiting the activation and expression of matrix metalloproteinase-9 and NF-kB activation; appears to enhance the anti-cancer activity of vitamin D (3) and its analogs.

★★Rye – Secale cereale (embryonic germinating seed-rootlets): Use as anti-estrogenic and antimutagenic for hormone-sensitive cancers of the prostate, bowel, and breast; for androgen hormone-dependent/independent cancers and other androgen conditions hyper or hypo functions. (Please refer to Silver Birch embryonic seeds to know more about plant growth, and immune and stress hormones.) Beta-1,3 glucans have been used in immuno-adjuvant therapy for cancer since 1980, primarily in Japan. Numerous studies report that beta-1, 3 glucans have anti-tumor and anti-cancer activity. In one study, intralesional administration of beta-1,3 glucans resulted in rapid tumor shrinkage. Rye extract is excellent in regulating autoimmune conditions, and studies have shown that it can also improve the symptoms of benign prostatic hyperplasia (BPH). Matairesinol is a lignan found in S. cereale that can be classified as phytoestrogenic, antiestrogenic, antimutagenic, and antiviral--properties all associated with plant lignans. Research reveals antioxidant capabilities of lignans.

Experimental trials involving humans, animals and in vitro experiments exhibit the protective effect lignans have against cancer and heart disease. Genistein is an isoflavone that can be classified as a phytoestrogen and has been widely studied for its anticancer properties. Research has shown that genistein can inhibit 5 alpha reductase and 17 beta-hydroxysteroid in vitro. It inhibits the metabolism of hormone-sensitive cancers of the prostate, bowel, and breast. The embryonic seed of rye contains great quantities of sterols and sterolins. Epidemiological studies also show that consumption of plant sterols reduces the risk of cancer of colon, prostate, ovary, stomach and breast. S. cereale reduces tumor incidence, slows tumor growth, and prevents cancer metastasis. Will effectively reduce the PSA at a dose of 10-15-30 drops 3 x a day.

★Silver Birch – Betula verrucosa (buds):

Phytochemical Constituents: The buds are balsamic and contain 4 to 6% of essential oil; also contain Acacetin, Apigenin, Auxins indole acetic acid IAA, Avicularin, Betulin, Betuloventic acid, Brassinosteroids (in much smaller quantity), Cubenol, Cytokinins, Dammarane sapogenins triterpenoids the content is less than that of the flower male catkins.

Renal – Uro Genital System: P B. verrucosa is a milder diuretic than the internal embryonic bark of the White Birch; stimulates and detoxifies the kidneys; for albuminuria, infectious urinary lithiasis, uricolytis, nephritis, pyelitis, And adult polycystic kidney disease. The buds hasten the removal of waste products in the urine, block the formation of uric acid and are beneficial for kidney stones and bladder stones, rheumatic conditions, and gout. With the help of papyriferic acid, a secondary metabolite of (dammarane-triterpenoids) on sapling twigs, prostate associated dysuria causes snowshoe hares (rabbits) to pass more sodium with their urine. This loss of sodium indicates birch’s defenses, including papyriferic acid, which are potential hypertension drugs. Only mature trees and embryonic buds of the Silver Birch contains papyriferic acid about 50%. But none is found in the White Birch buds B. pubescens.

Oncological Urology: P Acacetin (AC) has been shown to be effective against human prostate cancer (PCA). LNCaP cell line was established from a metastatic lesion of human prostatic adenocarcinoma and DU145 cells have moderate metastatic potential compared to PC3 cells, which have high metastatic potential. Betuloventic acid, as an anti-cancer drug has generated considerable interest. The compound has exhibited up to 96% inhibition of prostate tumor growth acid arrested mitosis and induced apoptosis. Synergy of various phytochemicals oncophytoembryonic therapy for prostate cancer.

★Silver Birch – Betula verrucosa (embryonic germinating seed-rootlets): Here you have an unsurpassed synergy of phytohormones, but the Brassinosteroids (sterols) are far more potent than the other hormones. The highest concentration of Brassinosteroids is found in the embryonic germinating seeds of Maize, Rye and Silver Birch seeds.

Prominent Phytochemical Constituents: Sesquiterpene Abscisic acid (ABA), Anthocyanins, Apigenins, Auxins Indoleacetic acid oxidase activity (IAA), Betulene and Betulenol, Brassinosteroids (BR) far more potent than the other hormones, (+)-catechin, Soluble condensed tannins, Chlorogenic acid, Cinnamic acid, Condensed Tannins, Cytokinins (CK), Ellagic acid, Ellagitannin, Flavan-3-ol, Gallic acid - Catechins, Gibberellins (GA), Jasmonates-Jasmonic acid (JA), Methyl jasmonate (MJA), Kaempferol, Meristems plant stem cells (PSC), Quercetin, Myricetin, Kaempferol, Phenylalanine, Phenolics.